Состояние тироидной системы у внутриутробно облученных детей и их матерей вследствие катастрофы на Чернобыльской АЭС

Abstract

The analysis of results of medical examination of women, pregnant at the time of the Chernobyl accident and their children is carried out. The autoimmune thyroiditis is diagnosed for mothers and their daughters. At sons the autoimmune thyroiditis wasn't diagnosed. The relative risk of development autoimmune thyroiditis in mothers (mother/ daughter) was statistically insignificant and was 2,36 (0,31÷14,18). The primary hypothyroidism is diagnosed for mothers and their daughters. At sons the primary hypothyroidism wasn't diagnosed. Frequency of occurrence of primary hypothyroidism was insignificantly when comparing between groups mother daughter (χ2=0,36 р=0,55). The relative risk of development primary hypothyroidism in mothers (mother/ daughter) was statistically insignificant and was 1,41 (0,55÷28,36). The relative risk of development of nodal goiter in mothers (mother/children) was statistically significant and was 3,07 (1,08÷9,44). The relative risk of development of nodal goiter (mother/daughter) was 9,64 (1,28÷72,4) and was statistically significant. Frequency of occurrence of primary hypothyroidism was significantly higher in children, whose term of a gestation at the time of Chernobyl accident was more than 14 weeks (in relation to children with gestational term less than 14 weeks).