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dc.contributor.authorLiang, Yongqiru
dc.contributor.authorLuan, Chunpengru
dc.contributor.authorWu, Yiru
dc.contributor.authorWu, Yangru
dc.contributor.authorSun, Pengshuru
dc.coverage.spatialМинскru
dc.date.accessioned2021-06-17T06:08:04Z
dc.date.available2021-06-17T06:08:04Z
dc.date.issued2021
dc.identifier.citationНаучная секция «Медицина. Санитария. Медицинская техника» = 新型比率荧光探针的制备与应用 / Yongqi Liang [и др.] // II Китайско-белорусский молодежный конкурс научно-исследовательских и инновационных проектов : сборник материалов конкурса, 20-21 мая 2021 г. / Белорусский национальный технический университет ; Научно-технологический парк БНТУ «Политехник» ; Институт Конфуция по науке и технике БНТУ. – Минск : БНТУ, 2021. – С. 165.ru
dc.identifier.urihttps://rep.bntu.by/handle/data/94772
dc.description.abstractAs a new type of nano-materials, metal nanoclusters have gained wide attention in chemistry, materials, biology and so on. In this project, the blue green fluorescent carbon nanomaterials with rich functional groups will be prepared by hydrothermal synthesis technology, using natural biomolecular bovine serum protein as precursor BSA@CDs. A new type of carbon nano coated silver nanoclustered composite was further prepared by using CDs as template (CDs@AgNCs). The prepared CDs was used as template to further prepare a new carbon nano-coated silver nanocluster composite (CDs@AgNCs). The prepared new composite CDs@AgNCs has a double emission signal with good separation degree, it can realize the visual detection of dopamine and copper ions by the change of fluorescence signal ratio, effectively eliminating the interference of environmental factors.ru
dc.language.isocnru
dc.publisherБНТУru
dc.titleНаучная секция «Медицина. Санитария. Медицинская техника»ru
dc.title.alternative新型比率荧光探针的制备与应用ru
dc.typeWorking Paperru
local.description.annotation目前我国人口老龄化处于持续发展时期,是对于慢性疾病、隐形疾病的移动医疗服 务需求巨大。大众的医疗理念也从之前“从不医检,病重就医”的转变为“预防为主,防 结合”。再加 之国家出台的一系列政策法规引导,近年来,大健康行业持续走高,体检行业的发展前景广阔。 多巴胺是一种神经传递介质,在人类免疫和神经系统中发挥着重要作用。铜离子广 泛地参与调控人体众多生物过程。因此,实时监控生物液体和细胞内多巴胺和铜离子的 含量是非常重要的。比率荧光探针是一种具有多个独立发射波段的荧光探针,可通过不 同峰强度比值的变化扩大动态响应的范围,同时有效减小了探针浓度和光源波动等因素 的干扰,实现对目标物质的更精确的分析。本项目制备出一种由蓝绿色荧光碳纳米粒子 修饰的银纳米簇复合材料,该材料具有分离度良好的双发射信号,通过荧光信号比值的 变化实现对多巴胺和铜离 的检测并通过配套使用的检测试剂盒实时分析和反馈。ru


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